It is produced mainly as a byproduct of acrylonitrile manufacture. This page provides supplementary chemical data on acetonitrile. If w b w f10, report breakthrough and possible sample loss. Treatment and disposal methods for waste chemicals irptc file. India veritas house, 70 mint road, fort, mumbai 400 001. Sheet msds, available from ineos, for information on the chemical. Wear appropriate protective face shield and eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910. Incompatible materials strong oxidizing agents, strong acids, reducing agents, bases hazardous decomposition productshydrogen cyanide hydrocyanic. Safety data sheet according to federal register vol. Cyanobearing indolinones by oxidative arylalkylation of olefins in the presence of palladium catalyst. Identification product identifier acetonitrile, distilled in glass other means of identification product code 1233 cas number 75058 synonyms ethane nitrile methyl cyanide cyanomethane professional, scientific and technical activities. P271 use only outdoors or in a wellventilated area. P280 wear eye protection, face protection, protective clothing, protective gloves. Hazards identification classification of the substance or mixture signal word.
Occupational exposure limits, if available, are listed in section 8. Acetonitrile decomposes when heated to produce deadly toxic hydrogen cyanide gas and oxides of. Here you will find all you need for administrative compliance to support your use of romil products. It is also a hazardous chemical substance and regulated as such throughout most of. Acetone safety data sheet according to federal register vol. Consider cyanide antidote as clinically indicated, such as sodium thiosulfate and sodium nitrate. Acetonitrile by dupont dated 032802 original location. Acetonitrile, also known as methyl cyanide or cyanomethane is a colorless chemical compound in liquid form having chemical formula ch 3 cn. May be harmful if swallowed, inhaled, or absorbed through the skin. More sds files for chemicals 75047 7504941 75051557 75056972 7505714 750590182 75059222 75062543 75070 75073119.
Acetonitrile revision date 17january2018 protective gear. The handling of this chemical may incur notable safety precautions. Material safety data sheet acetonitrile msds section 1. Accidental release measures personal precautions remove all sources of ignition. Acetonitrile is metabolized in the liver to water, formic acid, and hydrogen cyanide. Firstaid measures eyes rinse with plenty of water for at least 15 minutes and seek medical attention immediately. Chemical product and company identification product name. Seastar chemicals inc msds perchloric acid page 3 of 5 personal protective equipment eyes. Industrially, it is used as a solvent in the purification of butadiene and in the manufacturing of photographic film. Advancebio peptide chromatography columns with acetonitrile and water less than 10ml section 2. Material safety data sheet for acetonitrile, product number. Three volunteers were exposed for 4 hours at 40, 80, or 160 ppm acetonitrile. Acetonitrile is produced primarily as an acrylonitrile manufacture byproduct.
It is used as a polar aprotic solvent in organic synthesis and in the purification of butadiene. First aid measures eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Skin contact wash off immediately with plenty of water for at least 15 minutes. Acetonitrile hplc, fisher chemical fisher scientific. Fire hazard, acute health hazard, chronic health hazard 16. Show this safety data sheet to the doctor in attendance. It is highly recommend that you seek the material safety datasheet for this chemical.
Acetonitrile is a toxic, colorless liquid with an etherlike odor and a sweet, burnt taste. For extraction in fat and oil processing, fatty acids can. In industry, it is likewise used as a solvent for the manufacture of such products as pharmaceuticals. In a wellconducted study in mice, the oral ld50 of acetonitrile was calculated to be 617 mgkg. Common name acetonitrile english name acetonitrile cas number 75058 molecular weight 41. Acetonitrile acn is also known as cyanomethane or methyl cyanide. Hazards identification potential acute health effects. Inhalation move casualty to fresh air and keep at rest. Toxicity data oral rat 2,460 mgkg ld50 oral mouse 591 mgkg ld50 8 h inhalation rat,740 ppm lc50 4 h inhalation mouse 3,587 ppm lc50 skin rabbit 2,000 mgkg ld50 oral rat 2460 mgkg ld50 inhalation rat. Take precautionary measures against static discharges. Acetonitrile is the most basic and simple organic nitrile. Identification of the substancemixture and of the companyundertaking 1.
Acetonitrile is a clear, colorless liquid with a sweet, ethereal odor. Acetonitrile safety data sheet according to federal register vol. First aid measures general advice consult a physician. Further, acetonitrile can also be used as the solvent in the process of producing synthetic fiber and special paints. Calculate concentration, c, of acetonitrile in the air volume.
Ace acetic acid nitrile cyanomethane ethane nitrile ethyl nitrile methane carbonitrile methyl cyanide. Wear appropriate protective neoprene or polyethylene gloves to prevent skin exposure. Keep away from open flames, hot surfaces and sources of ignition. Acetonitrile market global industry analysis, size and. Acetonitrile is on the right to know hazardous substance. Acetonitrile revision date 17january2018 stability stable under normal conditions. It is an extremely dangerous substance and must be handled with caution as it can cause severe health effects andor death. Other information revision b, june 2015 the information contained herein is provided in good faith and is believed to be correct as of the date hereof. Acetonitrile ch 3 cn, cas 75058, also known as methyl cyanide or cyanomethane, is the simplest organic nitrile. Upload files that contain software or other material protected by intellectual property laws or by rights of privacy of publicity unless you own or control the rights thereto or have received all necessary consents. Hazards identification medical conditions aggravated by overexposure preexisting disorders involving any target organs mentioned in this msds as being at risk may be aggravated by overexposure to this product no known significant effects or critical hazards.
Mecn is utilized as a mobile phase component in many chromatographic techniques. Registration number 75 05 8 200 835 2 608 001 00 3 01 2119477 38 xxxx 4. Acetonitrile, an aliphatic nitrile, is widely used as an organic solvent and intermediate in organic syntheses. Some relevant physical and chemical properties of acn are listed below who, 1993. Acetonitrile cas no 75058 material safety data sheet. Incompatible materials strong oxidizing agents, strong acids, reducing agents, bases hazardous decomposition productshydrogen cyanide hydrocyanic acid, nitrogen oxides nox. Safety data sheet sds acetonitrile, 15% solution 01. Produced mainly as a byproduct of manufacturing acrylonitrile, acetonitrile is a colorless liquid with an etherlike odor. Firstaid measures inhalation remove victim to fresh air and keep at rest in a position comfortable for breathing. Acetonitrile is the chemical compound with the formula ch 3 cn. This colourless liquid is the simplest organic nitrile hydrogen cyanide is a simpler nitrile, but the cyanide anion is not classed as organic.
Upload files that contain viruses, corrupted files, or any other similar software or. Acetonitrile 75058 100 toxicological data on ingredients. Acetonitrile in water 20%, s4b thermo fisher scientific. It is also a hazardous chemical substance and regulated as such throughout most of the world. Sigmaaldrich material safety data sheet product name. If inhaled if breathed in, move person into fresh air.
Material safety data sheet acetonitrile section 1 chemical product and company identification msds name. This reagent is intended for nterminal protein sequencing applications. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Thermal decomposition can lead to release of irritating gases and vapors. H373 may cause damage to organs through prolonged or repeated.
Adg acetonitrile solution ab sciex australia pty ltd po box 514. At 40 ppm, odor was detected, after which olfactory fatigue was noted. It is transparent to uvvisible light, which makes it highly applicable in spectrophotometric and fluorimetric techniques. Relevant identified uses of the substance or mixture and uses advised against.
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